Category: Lupus News
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Phenotyping of P105-negative B cell subsets in patients with systemic lupus erythematosus.
Phenotyping of P105-negative B cell subsets in patients with systemic lupus erythematosus. Clin Dev Immunol. 2012;2012:198206 Authors: Koarada S, Tada Y, Suematsu R, Soejima S, Inoue H, Ohta A, Nagasawa K Abstract This study aimed to investigate phenotype of RP105(-) B cell subsets in patients with systemic lupus erythematosus (SLE). Flow cytometry was used for…
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Systemic lupus erythematosus and Graves’ disease in Thai population
Association between CTLA-4 polymorphisms and the susceptibility to systemic lupus erythematosus and Graves’ disease in Thai population. Asian Pac J Allergy Immunol. 2011 Sep;29(3):229-35 Authors: Kimkong I, Nakkuntod J, Sae-Ngow S, Snabboon T, Avihingsanon Y, Hirankarn N Abstract BACKGROUND: Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is a cell surface molecule involved in the regulation of T cells.…
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A proposed model for physiologic and pathologic regulation in systemic lupus erythematosus.
Adenosine inhibits the release of arachidonic acid in activated human peripheral mononuclear cells. A proposed model for physiologic and pathologic regulation in systemic lupus erythematosus. ScientificWorldJournal. 2011;11:972-80 Authors: Sipka S Abstract In the current work, the pathways are presented and reviewed showing how adenosine acts on the production and release of arachidonic acid (AA) in…
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Autoimmune Syndrome Induced by Adjuvants (ASIA) in the Middle East: morphea following silicone implantation
S Kivity1,2,3⇓ M Katz3 P Langevitz1,2 I Eshed4 D Olchovski3 A Barzilai5 1Rheumatology Unit, Sheba Medical Center, Tel-Hashomer, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel 2Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel 3Department of Medicine ‘A’, Sheba Medical Center, Tel-Hashomer, affiliated…
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Th subset balance in lupus nephritis.
Th subset balance in lupus nephritis. J Biomed Biotechnol. 2011;2011:980286 Authors: Miyake K, Akahoshi M, Nakashima H Abstract Lupus nephritis, which has various histological patterns and variable clinical outcomes, is one of the most important complications of systemic lupus nephritis (SLE). This pathogenetic mechanism in each histologically different type of lupus nephritis (LN) remains unclear.…
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Myocardial perfusion defects in systemic lupus erythematosus patients.
Influence of chronic inflammation and autoimmunity on coronary calcifications and myocardial perfusion defects in systemic lupus erythematosus patients. Inflamm Res. 2011 Oct;60(10):973-80 Authors: Plazak W, Pasowicz M, Kostkiewicz M, Podolec J, Tomkiewicz-Pajak L, Musial J, Podolec P Abstract OBJECTIVE: Conventional risk factors for coronary artery disease fail to explain the increased frequency or cardiovascular morbidity…
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Link between autoimmune diseases and wounds that don’t heal examined
Millions of Americans suffer from wounds that don’t heal, and while most are typically associated with diabetes, new research has identified another possible underlying cause – autoimmune diseases. The finding represents an unappreciated link that could lead to important new insights in wound healing, say researchers.
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MMF Found Superior to Azathioprine for Lupus Nephritis Maintenance
A new large, international study has found that the immunosuppressant drug mycophenolate mofetil (MMF) is superior to azathioprine as a maintenance therapy for patients with lupus nephritis. John Schieszer reports in today’s Medical Minute that lupus nephritis patients appear to respond to MMF for a longer period o Full story
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Stranger’s Kindness Gives Children of Lupus Sufferer a Merry Christmas
Like many people struggling with the financial consequences of being unable to work because of lupus, one Chicago lupus sufferer was pinching pennies to buy her grandchildren each a present. A truly “Secret” Santa came to her rescue to ensure that those children had presents from grandma. All of you who donate to lupus are…
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Pattern of systemic lupus erythematosus in Egyptian patients: the impact of disease activity on the quality of life.
Pattern of systemic lupus erythematosus in Egyptian patients: the impact of disease activity on the quality of life. Pan Afr Med J. 2010;6:14 Authors: Sliem H, Tawfik G, Khalil KA, Ibrahim N Abstract INTRODUCTION: Systemic lupus erythematosus (SLE) afflicts young people disproportionately, often at a crucial time in their lives when they are trying to…