Category: Lupus News
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Systemic Lupus Erythematosus Disease Activity Index-2000
The use of Systemic Lupus Erythematosus Disease Activity Index-2000 to define active disease and minimal clinically meaningful change based on data from a large cohort of systemic lupus erythematosus patients. Rheumatology (Oxford). 2011 May;50(5):982-8 Authors: Yee CS, Farewell VT, Isenberg DA, Griffiths B, Teh LS, Bruce IN, Ahmad Y, Rahman A, Prabu A, Akil M,…
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New Trial Testing Benlysta as Injectable
The Lupus Research Institute is pleased to alert people with lupus of a new Phase III trial testing the efficacy, safety and tolerability of the recently approved Benlysta(r) as a once-a-week injectable rather than the existing intravenous formulation. For more information, visit clinicaltrials.gov and search for trial NCT01484496. Full story
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Amelioration of lupus nephritis by serum
Amelioration of lupus nephritis by serum amyloid P component gene therapy with distinct mechanisms varied from different stage of the disease. PLoS One. 2011;6(7):e22659 Authors: Zhang W, Wu J, Qiao B, Xu W, Xiong S Abstract BACKGROUND: Our previous study revealed that administration of syngeneic female BALB/c mice with excessive self activated lymphocyte-derived DNA (ALD-DNA)…
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Two infrequent complications of systemic lupus erythematosus.
Hemorrhagic cholecystitis and hemobilia: two infrequent complications of systemic lupus erythematosus. Rev Esp Enferm Dig. 2011 Aug;103(8):431-3 Authors: García Pérez R, Ruiz de Angulo D, López Poveda MJ, Febrero Sánchez B, Navas Carrillo D, Parrilla Paricio P Abstract INTRODUCTION: the patients affected by systemic lupus erythematosus (SLE) often suffer gastrointestinal symptoms. The differential diagnosis…
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Interferon-inducible gene 202b controls CD8(+) T cell-mediated suppression in anti-DNA Ig peptide-treated (NZB × NZW) F1 lupus mice.
Interferon-inducible gene 202b controls CD8(+) T cell-mediated suppression in anti-DNA Ig peptide-treated (NZB × NZW) F1 lupus mice. Genes Immun. 2011 Jul;12(5):360-9 Authors: Dinesh R, Hahn BH, La Cava A, Singh RP Abstract Administration of an artificial peptide (pConsensus) based on anti-DNA IgG sequences that contain major histocompatibility complex class I and class II T-cell…
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Systemic diseases and the pleura.
Systemic diseases and the pleura. Arch Bronconeumol. 2011 Jul;47(7):361-70 Authors: Ferreiro L, Alvarez-Dobaño JM, Valdés L Abstract Pleural involvement in systemic diseases is usually a sign of lesions occurring at other levels. Despite the low incidence (around 1%) of pleural effusions caused by systemic diseases, more often connective tissue diseases, such as rheumatoid arthritis or…
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High prevalence of hypovitaminosis D in a Swiss rheumatology outpatient population.
High prevalence of hypovitaminosis D in a Swiss rheumatology outpatient population. Swiss Med Wkly. 2011;141:w13196 Authors: Stoll D, Dudler J, Lamy O, Hans D, So A, Krieg MA, Aubry-Rozier B Abstract Vitamin D is important for bone metabolism and neuromuscular function. While a routine dosage is often proposed in osteoporotic patients, it is not so…
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Pandemic influenza A/H1N1 virus in a patient with systemic lupus erythematosus.
Pandemic influenza A/H1N1 virus in a patient with systemic lupus erythematosus. Rev Inst Med Trop Sao Paulo. 2011 Jun;53(3):177 Authors: Bonin CC, Silva BS, Carvalho JF PMID: 21755242 [PubMed – indexed for MEDLINE]
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Common variable immunodeficiency associated with hepatosplenic T-cell lymphoma mimicking juvenile systemic lupus erythematosus.
Common variable immunodeficiency associated with hepatosplenic T-cell lymphoma mimicking juvenile systemic lupus erythematosus. Clin Dev Immunol. 2011;2011:428703 Authors: Jesus AA, Jacob CM, Silva CA, Dorna M, Pastorino AC, Carneiro-Sampaio M Abstract Common variable immunodeficiency (CVID) is a heterogeneous disorder with susceptibility to infections, autoimmune manifestations, and cancer. To our knowledge, CIVD with T-cell lymphoma mimicking…
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Plasma concentrations of Gas6 and sAxl correlate with disease activity in systemic lupus erythematosus.
Plasma concentrations of Gas6 and sAxl correlate with disease activity in systemic lupus erythematosus. Rheumatology (Oxford). 2011 Jun;50(6):1064-9 Authors: Ekman C, Jönsen A, Sturfelt G, Bengtsson AA, Dahlbäck B Abstract OBJECTIVES: SLE is a systemic autoimmune disease with an annual incidence of 3.8 per 100,000. Several pathogenic mechanisms are believed to be operating in SLE,…